Targeting PD-L1 and TIGIT could restore intratumoral CD8 T cell function in human colorectal cancer. Cancer immunology, immunotherapy : CII, 10.1007/s00262-022-03182-9. Advance online publication.
Our publications
Since its creation, Institut Roche has translated its expertise into numerous successful scientific publications
CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles. Br J Cancer 125, 1687–1698 (2021).
Aitamer, M., Akil, H., Vignoles, C. et al.
https://doi.org/10.1038/s41416-021-01611-7Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from a 2-year longitudinal follow-up study (InFoR). Molecular autism, 12(1), 71.
Amestoy, A., Guillaud, E., Bucchioni, G., Zalla, T., Umbricht, D., Chatham, C., Murtagh, L., Houenou, J., Delorme, R., Moal, M. L., Leboyer, M., Bouvard, M., & Cazalets, J. R. (2021).
https://doi.org/10.1186/s13229-021-00474-2Tetraspanin8 expression predicts an increased metastatic risk and is associated with cancer-related death in human cutaneous melanoma. Molecular cancer, 20(1), 127.
Berthier-Vergnes, O., Barbollat-Boutrand, L., Pommier, R. M., de la Fouchardière, A., Combemale, P., Grimont, M., Lopez-Ramirez, N., Caramel, J., Dalle, S., Perrot, J. L., Gaudy-Marqueste, C., Macagno, N., Mansard, S., Bouquet, F., & Masse, I. (2021).
https://doi.org/10.1186/s12943-021-01429-0Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science immunology, 6(62), eabl4340.
Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Manry, J., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., de Prost, N., Tandjaoui-Lambiotte, Y., Luyt, C. E., … Casanova, J. L. (2021).
https://doi.org/10.1126/sciimmunol.abl4340Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection. Science advances, 7(34), eabg4081.
Yatim, N., Boussier, J., Tetu, P., Smith, N., Bruel, T., Charbit, B., Barnabei, L., Corneau, A., Da Meda, L., Allayous, C., Baroudjian, B., Jebali, M., Herms, F., Grzelak, L., Staropoli, I., Calmettes, V., Hadjadj, J., Peyrony, O., Cassius, C., LeGoff, J., … Lebbé, C. (2021).
https://doi.org/10.1126/sciadv.abg4081Discriminant value of repetitive behaviors in families with autism spectrum disorder and obsessional compulsive disorder probands. Autism research : official journal of the International Society for Autism Research, 14(11), 2373–2382.
Lefebvre, A., Cohen, A., Maruani, A., Amsellem, F., Beggiato, A., Amestoy, A., Moal, M. L., Umbricht, D., Chatham, C., Murtagh, L., Bouvard, M., Leboyer, M., Bourgeron, T., & Delorme, R. (2021).
https://doi.org/10.1002/aur.2570Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death. PLOS Computational Biology, 17(3), e1008870.
Veith, I., Mencattini, A., Picant, V., Serra, M., Leclerc, M., Comes, M. C., Mami-Chouaib, F., Camonis, J., Descroix, S., Shirvani, H., Mechta-Grigoriou, F., Zalcman, G., Parrini, M. C., & Martinelli, E. (2021).
https://doi.org/10.1371/journal.pcbi.1008870The Caspase-1/IL-18 Axis of the Inflammasome in Tumor Cells: A Modulator of the Th1/Tc1 Response of Tumor-Infiltrating T Lymphocytes in Colorectal Cancer. Cancers, 13(2), 189.