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Since its creation, Institut Roche has translated its expertise into numerous successful scientific publications

Dos Santos Q, Leung P, Thorball CW, Ledergerber B, Fellay J, MacPherson CR, Hornum M, Terrones-Campos C, Rasmussen A, Gustafsson F, Perch M, Sørensen SS, Ekenberg C, Lundgren JD, Feldt-Rasmussen B, Reekie J. (2023)

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort Front Mol Biosci. 10:1282412

https://doi.org/10.3389/fmolb.2023.1282412

Hammoudi N, Hamoudi S, Bonnereau J, Bottois H, Pérez K, Bezault M, Hassid D, Chardiny V, Grand C, Gergaud B, Bonnet J, Chedouba L, Tran Minh ML, Gornet JM, Baudry C, Corte H, Maggiori L, Toubert A, McBride J, Brochier C, Neighbors M, Le Bourhis L, Allez M. (2022).

Autologous organoid co-culture model reveals T cell-driven epithelial cell death in Crohn’s Disease Front Immunol. 13:1008456

https://doi.org/10.3389/fimmu.2022.1008456

Thibaudin, M., Limagne, E., Hampe, L., Ballot, E., Truntzer, C., & Ghiringhelli, F. (2022).

Targeting PD-L1 and TIGIT could restore intratumoral CD8 T cell function in human colorectal cancer. Cancer immunology, immunotherapy : CII, 10.1007/s00262-022-03182-9. Advance online publication.

https://doi.org/10.1007/s00262-022-03182-9

Aitamer, M., Akil, H., Vignoles, C. et al.

CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles. Br J Cancer 125, 1687–1698 (2021).

https://doi.org/10.1038/s41416-021-01611-7

Amestoy, A., Guillaud, E., Bucchioni, G., Zalla, T., Umbricht, D., Chatham, C., Murtagh, L., Houenou, J., Delorme, R., Moal, M. L., Leboyer, M., Bouvard, M., & Cazalets, J. R. (2021).

Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from a 2-year longitudinal follow-up study (InFoR). Molecular autism, 12(1), 71.

https://doi.org/10.1186/s13229-021-00474-2

Berthier-Vergnes, O., Barbollat-Boutrand, L., Pommier, R. M., de la Fouchardière, A., Combemale, P., Grimont, M., Lopez-Ramirez, N., Caramel, J., Dalle, S., Perrot, J. L., Gaudy-Marqueste, C., Macagno, N., Mansard, S., Bouquet, F., & Masse, I. (2021).

Tetraspanin8 expression predicts an increased metastatic risk and is associated with cancer-related death in human cutaneous melanoma. Molecular cancer, 20(1), 127.

https://doi.org/10.1186/s12943-021-01429-0

Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Manry, J., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., de Prost, N., Tandjaoui-Lambiotte, Y., Luyt, C. E., … Casanova, J. L. (2021).

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science immunology, 6(62), eabl4340.

https://doi.org/10.1126/sciimmunol.abl4340

Yatim, N., Boussier, J., Tetu, P., Smith, N., Bruel, T., Charbit, B., Barnabei, L., Corneau, A., Da Meda, L., Allayous, C., Baroudjian, B., Jebali, M., Herms, F., Grzelak, L., Staropoli, I., Calmettes, V., Hadjadj, J., Peyrony, O., Cassius, C., LeGoff, J., … Lebbé, C. (2021).

Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection. Science advances, 7(34), eabg4081.

https://doi.org/10.1126/sciadv.abg4081

Lefebvre, A., Cohen, A., Maruani, A., Amsellem, F., Beggiato, A., Amestoy, A., Moal, M. L., Umbricht, D., Chatham, C., Murtagh, L., Bouvard, M., Leboyer, M., Bourgeron, T., & Delorme, R. (2021).

Discriminant value of repetitive behaviors in families with autism spectrum disorder and obsessional compulsive disorder probands. Autism research : official journal of the International Society for Autism Research, 14(11), 2373–2382.

https://doi.org/10.1002/aur.2570
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