Natural history of Type 2 and 3 spinal muscular atrophy: 2-year NatHis-SMA study. Annals of clinical and translational neurology, 8(2), 359–373.
Our publications
Since its creation, Institut Roche has translated its expertise into numerous successful scientific publications
DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity. Biorxiv.
Sauvaigo, S., Benkhiat, M., Braisaz, F., Girard, J., Libert, S., Mouret, S., de Fraipont, F., Aspord, C., Bouquet, F., & Leccia, M. T. (2020).
https://doi.org/10.1101/2020.04.29.067900Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment. Journal of pharmacokinetics and pharmacodynamics, 47(6), 613–625.
Mercier, F., Kerioui, M., Desmée, S., Guedj, J., Krieter, O., & Bruno, R. (2020).
https://doi.org/10.1007/s10928-020-09714-zBayesian inference using Hamiltonian Monte-Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy. Statistics in medicine, 39(30), 4853–4868.
Kerioui, M., Mercier, F., Bertrand, J., Tardivon, C., Bruno, R., Guedj, J., & Desmée, S. (2020).
https://doi.org/10.1002/sim.8756“Reading the Mind in the Eyes” in Autistic Adults is Modulated by Valence and Difficulty : An InFoR Study. Autism Research, 14(2), 380-388.
Baltazar, M., Geoffray, M., Chatham, C., Bouvard, M., Martinez Teruel, A., Monnet, D., Scheid, I., Murzi, E., Couffin-Cadiergues, S., Umbricht, D., Murtagh, L., Delorme, R., Ly Le-Moal, M., Leboyer, M., & Amestoy, A. (2020).
https://doi.org/10.1002/aur.2390Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways. Cell Death Discovery, 6(1).
Vial, J., Huchedé, P., Fagault, S., Basset, F., Rossi, M., Geoffray, J., Soldati, H., Bisaccia, J., Elsensohn, M. H., Creveaux, M., Neves, D., Blay, J. Y., Fauvelle, F., Bouquet, F., Streichenberger, N., Corradini, N., Bergeron, C., Maucort-Boulch, D., Castets, P.,. . . Castets, M. (2020).
https://doi.org/10.1038/s41420-020-00302-1IDO Targeting in Sarcoma : Biological and Clinical Implications. Frontiers in Immunology, 11.
Nafia, I., Toulmonde, M., Bortolotto, D., Chaibi, A., Bodet, D., Rey, C., Velasco, V., Larmonier, C. B., Cerf, L., Adam, J., le Loarer, F., Savina, A., Bessede, A., & Italiano, A. (2020).
https://doi.org/10.3389/fimmu.2020.00274Prototyping Trastuzumab Docetaxel Immunoliposomes with a New FCM-Based Method to Quantify Optimal Antibody Density on Nanoparticles. Sci Rep 10, 4147 (2020).
Rodallec, A., Franco, C., Robert, S. et al.
https://doi.org/10.1038/s41598-020-60856-zTumor uptake and associated greater efficacy of anti-Her2 immunoliposome does not rely on Her2 expression status: study of a docetaxel-trastuzumab immunoliposome on Her2+ breast cancer model (SKBR3). Anti-cancer drugs, 31(5), 463–472.