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Our publications

Since its creation, Institut Roche has translated its expertise into numerous successful scientific publications

B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis. Frontiers in immunology, 8, 53.

Sanges, S., Jendoubi, M., Kavian, N., Hauspie, C., Speca, S., Crave, J. C., Guerrier, T., Lefèvre, G., Sobanski, V., Savina, A., Hachulla, E., Hatron, P. Y., Labalette, M., Batteux, F., Dubucquoi, S., & Launay, D. (2017).

https://doi.org/10.3389/fimmu.2017.00053
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Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101. Leukemia research, 55, 41-48.

Chien, W. W., Niogret, C., Jugé, R., Lionnard, L., Cornut-Thibaut, A., Kucharczak, J., Savina, A., Salles, G., & Aouacheria, A. (2017).

https://doi.org/10.1016/j.leukres.2017.01.010
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The RAS -related GTP ase RHOB confers resistance to EGFR -tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT -dependent mechanism. EMBO Molecular Medicine, 9(2), 238-250.

Calvayrac, O., Mazières, J., Figarol, S., Marty-Detraves, C., Raymond-Letron, I., Bousquet, E., Farella, M., Clermont-Taranchon, E., Milia, J., Rouquette, I., Guibert, N., Lusque, A., Cadranel, J., Mathiot, N., Savina, A., Pradines, A., & Favre, G. (2016).

https://doi.org/10.15252/emmm.201606646
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Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies. Sci Rep 6, 34382 (2016).

Grandjean, C., Montalvao, F., Celli, S. et al.

https://doi.org/10.1038/srep34382
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High-MET status in non-small cell lung tumors correlates with receptor phosphorylation but not with the serum level of soluble form. Lung Cancer, 101, 59-67.

Copin, M. C., Lesaffre, M., Berbon, M., Doublet, L., Leroy, C., Tresch, E., Porte, H., Vicogne, J., B. Cortot, A., Dansin, E., & Tulasne, D. (2016).

https://doi.org/10.1016/j.lungcan.2016.09.009
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Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization. PloS one, 11(7), e0157670.

Vallerand, D., Massonnet, G., Kébir, F., Gentien, D., Maciorowski, Z., De la Grange, P., Sigal-Zafrani, B., Richardson, M., Humbert, S., Thuleau, A., Assayag, F., de Plater, L., Nicolas, A., Scholl, S., Marangoni, E., Weigand, S., Roman-Roman, S., Savina, A., & Decaudin, D. (2016).

https://doi.org/10.1371/journal.pone.0157670
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Tracking Cancer Genetic Evolution using OncoTrack. Sci. Rep. 6,29647;

Talukder, A. K. et al. (2016).

https://doi.org/10.1038/srep29647
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Similar white matter but opposite grey matter changes in schizophrenia and high-functioning autism. Acta Psychiatrica Scandinavica, 134(1), 31-39.

Katz, J., D’Albis, M. A., Boisgontier, J., Poupon, C., Mangin, J. F., Guevara, P., Duclap, D., Hamdani, N., Petit, J., Monnet, D., le Corvoisier, P., Leboyer, M., Delorme, R., & Houenou, J. (2016).

https://doi.org/10.1111/acps.12579
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Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma. European journal of nuclear medicine and molecular imaging, 43(4), 682–694.

Corroyer-Dulmont, A., Pérès, E. A., Gérault, A. N., Savina, A., Bouquet, F., Divoux, D., Toutain, J., Ibazizène, M., MacKenzie, E. T., Barré, L., Bernaudin, M., Petit, E., & Valable, S. (2016).

https://doi.org/10.1007/s00259-015-3225-0
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