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Nos publications

Depuis sa création, l’Institut Roche a mis son expertise au profit de nombreuses publications scientifiques.

Buatois, S., Retout, S., Frey, N. et al.

Item Response Theory as an Efficient Tool to Describe a Heterogeneous Clinical Rating Scale in De Novo Idiopathic Parkinson’s Disease Patients. Pharm Res 34, 2109–2118 (2017).

https://doi.org/10.1007/s11095-017-2216-1

Poli, C., Augusto, J. F., Dauvé, J., Adam, C., Preisser, L., Larochette, V., Pignon, P., Savina, A., Blanchard, S., Subra, J. F., Chevailler, A., Procaccio, V., Croué, A., Créminon, C., Morel, A., Delneste, Y., Fickenscher, H., & Jeannin, P. (2017).

IL-26 Confers Proinflammatory Properties to Extracellular DNA. Journal of immunology (Baltimore, Md. : 1950), 198(9), 3650–3661.

https://doi.org/10.4049/jimmunol.1600594

Sanges, S., Jendoubi, M., Kavian, N., Hauspie, C., Speca, S., Crave, J. C., Guerrier, T., Lefèvre, G., Sobanski, V., Savina, A., Hachulla, E., Hatron, P. Y., Labalette, M., Batteux, F., Dubucquoi, S., & Launay, D. (2017).

B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis. Frontiers in immunology, 8, 53.

https://doi.org/10.3389/fimmu.2017.00053

Chien, W. W., Niogret, C., Jugé, R., Lionnard, L., Cornut-Thibaut, A., Kucharczak, J., Savina, A., Salles, G., & Aouacheria, A. (2017).

Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101. Leukemia research, 55, 41-48.

https://doi.org/10.1016/j.leukres.2017.01.010

Calvayrac, O., Mazières, J., Figarol, S., Marty-Detraves, C., Raymond-Letron, I., Bousquet, E., Farella, M., Clermont-Taranchon, E., Milia, J., Rouquette, I., Guibert, N., Lusque, A., Cadranel, J., Mathiot, N., Savina, A., Pradines, A., & Favre, G. (2016).

The RAS -related GTP ase RHOB confers resistance to EGFR -tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT -dependent mechanism. EMBO Molecular Medicine, 9(2), 238-250.

https://doi.org/10.15252/emmm.201606646

Grandjean, C., Montalvao, F., Celli, S. et al.

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies. Sci Rep 6, 34382 (2016).

https://doi.org/10.1038/srep34382

Copin, M. C., Lesaffre, M., Berbon, M., Doublet, L., Leroy, C., Tresch, E., Porte, H., Vicogne, J., B. Cortot, A., Dansin, E., & Tulasne, D. (2016).

High-MET status in non-small cell lung tumors correlates with receptor phosphorylation but not with the serum level of soluble form. Lung Cancer, 101, 59-67.

https://doi.org/10.1016/j.lungcan.2016.09.009

Vallerand, D., Massonnet, G., Kébir, F., Gentien, D., Maciorowski, Z., De la Grange, P., Sigal-Zafrani, B., Richardson, M., Humbert, S., Thuleau, A., Assayag, F., de Plater, L., Nicolas, A., Scholl, S., Marangoni, E., Weigand, S., Roman-Roman, S., Savina, A., & Decaudin, D. (2016).

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization. PloS one, 11(7), e0157670.

https://doi.org/10.1371/journal.pone.0157670

Talukder, A. K. et al. (2016).

Tracking Cancer Genetic Evolution using OncoTrack. Sci. Rep. 6,29647;

https://doi.org/10.1038/srep29647
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